Edward P. Evans MDS Fellow · Columbia University
M.D.M.Sc.Ph.D.
Physician-scientist decoding how the three-dimensional genome decides the fate of blood stem cells, and what goes wrong in leukemia.
Now obsessed with chromatin loops
Citation metrics from Google Scholar, as of September 2026.
01Research
Trained first as a physician, then in the wet lab, then in code. Four threads run through my work, and all of them start from patients.
01Current focus · Columbia
How does genome folding decide what a hematopoietic stem cell becomes? I lead the computational and multi-omics analyses of STAG2-cohesin in blood formation and myeloid leukemia, integrating 3D genome maps with chromatin accessibility, protein–DNA binding, DNA methylation and single-cell profiles. Key Personnel on an NIH/NCI R37 MERIT Award.
02Ph.D. · Karolinska Institutet
Sarcomas are rare and strikingly heterogeneous. I built end-to-end pipelines integrating transcriptomic, genomic, epigenomic and proteomic data to define molecular subtypes, treatment-resistance mechanisms and prognostic biomarkers in synovial sarcoma, Ewing sarcoma and chondrosarcoma, and lately how epigenetic remodeling opens sarcomas to T cells.
03Computational oncology
Prognostic and multi-modal models that combine multi-omics, clinical and imaging data to predict outcomes, now in myeloid malignancy cohorts. I also build LLM-based, tool-using agents for reproducible analysis pipelines, with retrieval-augmented generation and strict evaluation: unit tests, data-leakage and sensitivity checks.
04Team science
Leading the bioinformatics in multidisciplinary teams, from natural killer cell states and the tumor microenvironment to metastatic dormancy, in work published in Nature Cell Biology, Science Translational Medicine and the JCI.
02Journey
27.99°N · 120.70°E
2009 – 2014 · China
M.D., Wenzhou Medical University
Clinical medicine, with rotations at the First Affiliated Hospital and community health outreach.
25.27°N · 110.29°E
2014 – 2017 · China
M.Sc. in Urology, Guilin Medical University
Urology residency alongside research on long non-coding RNAs and FISH-based prognosis in bladder cancer.
59.33°N · 18.07°E
2017 – 2022 · Sweden
Ph.D., Karolinska Institutet
Oncology-Pathology: multi-omics of Ewing and synovial sarcoma, then quantitative proteomics at SciLifeLab.
40.84°N · 73.94°W
2022 – now · USA
Postdoctoral Research Scientist, Columbia University Irving Medical Center
Chromatin architecture in hematopoietic stem cells and leukemia, in the lab of Dr. Aaron Viny. Edward P. Evans MDS Fellow.
04Recognition
$50,000
Edward P. Evans Foundation · 2026–2027
R37 · MERIT
The role of the cohesin complex in hematopoietic transformation and leukemia maintenance · PI: Aaron D. Viny · 2023–2028
05Toolkit
I design the experiment, run it, and write the pipeline that analyses it.
06Service
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Languages MandarinEnglish
07Contact
Columbia University Irving Medical Center · New York, NY